Hydrolyzed, Autolyzed, and Other MSG-Containing Ingredients In Foods and Vaccines Kick-Start Schizophrenia

April 24, 2013 | By Dylan Charles

Dave Mihalovic, Prevent Disease – Waking Times

WIKI-MSG1Glutamate is everywhere. It’s in food, medicine, vaccines, spices, and even household cleaning agents. It’s very toxic to the brain of any mammal at any age. New evidence suggests excess glutamate causes a progression of schizophrenia and related psychotic disorders.

The human brain is packed with a substance that needs to be treated like a handle-with-care explosive. Glutamate, one of the most abundant chemical messengers in the brain, plays a role in many vital brain functions, such as learning and memory, but it can inflict massive damage if it is accidentally spilled into brain tissue in large amounts.

Glutamate flow in the brain is normally kept in check by a system of dam-like structures, which release a trickle of the substance only when and where it is needed. But burst a dam–as happens in stroke, head trauma, and some other neurological disorders–and the treacherous messenger floods the brain. The surge of glutamate radiates out from the area of original damage, and kills neurons in nearby areas. The expanded damage can leave in its wake signs of impaired brain function, such as slurred speech and shaky movement.

Glutamate in Food

Monosodium Glutamate (MSG) is not a nutrient, vitamin, or mineral and has no health benefits. The part of MSG that negatively affects the human body is the “glutamate”, not the sodium. The breakdown of MSG typically consists of 78% glutamate, 12% sodium, and about 10% water. Any glutamate added to a processed food is not and can not be considered naturally occurring. Natural glutamate in plants and animals is known as L-glutamic acid.

 
In contrast, processed free glutamic acid (MSG) contains both L-glutamic acid and D-glutamic acid, and is also accompanied by pyroglutamic acid and other impurities. The impurities differ according to the starting materials and methods used to produce the glutamic acid (MSG). It is only acid hydrolyzed proteins that contain mono and dichloro propanols (which are carcinogenic), and it is only reaction flavors that contain heterocyclic amines (which are also carcinogenic).

By FDA definition, processed free glutamic acid (MSG) is “naturally occurring,” because the basic ingredients are found in nature. “Naturally occurring” does not mean that a food additive is being used in its natural state. “Naturally occurring” only means that the food additive began with something found in nature. By FDA definition, the ingredient “monosodium glutamate” is natural. So is hydrochloric acid. So is arsenic. “Natural” doesn’t mean “safe.”

Processed free glutamic acid (MSG) is created when protein is either partially or fully broken apart into its constituent amino acids, or glutamic acid is secreted from selected bacteria. A protein can be broken into its constituent amino acids in a number of ways (autolysis, hydrolysis, enzymolysis, and/or fermentation). When a protein is broken down, the amino acid chains in the protein are broken, and individual amino acids are freed. These processes are discussed in some detail in food encyclopedias — wherein articles on glutamic acid and “monosodium glutamate” are generally written by persons who work for Ajinomoto, Co., Inc., the world’s largest producer of the food ingredient “monosodium glutamate.”

It used to be that when any ingredient contained 78%-79% processed free glutamic acid (MSG), and the balance was made up of salt, moisture, and up to 1 per cent impurities, the FDA required that the product be called “monosodium glutamate”, and required that the product be labeled as such. The FDA required that other MSG-containing ingredients be identified by names other than “monosodium glutamate.” Never has the FDA required mention of the fact that an ingredient contains processed free glutamic acid (MSG).

While the glutamic acid in “monosodium glutamate” is generally produced through bacterial fermentation, the glutamic acid in the other MSG-containing ingredients is made through use of chemicals (hydrolysis or autolysis), enzymes (enzymolysis), fermentation, or a complex cooking process wherein reaction flavors are produced from a combination of specific amino acids, reducing sugars, animal or vegetable fats or oils, and optional ingredients including hydrolyzed vegetable protein.

It is now essentially unregulated when it comes to labeling standards. A label may say “yeast extract“, “calcium caseinate”, or “beef flavoring”, but the product still contains varying amounts of “free” glutamic acid. This makes it very difficult for consumers who are trying to avoid it. It is also very dangerous for those who suffer severe reactions to it. Many people who are very sensitive to MSG experience respiratory, neurological, muscular, skin, urological and even cardiac symptoms.

Some of the common ingredients which contain MSG are: Plant Protein, Hydrolyzed Corn Gluten, Hydrolyzed Pea Protein, Textured Protein, Autolyzed Yeast Extract, Autolyzed Plant Protein, Yeast Extract, Calcium Caseinate, Sodium Caseinate, Gelatin, Disodium Guanylate, Disodium Inosinate, Carrageenan, Xanthum Gum, Maltodextrin, Natural Flavor, Barley Malt, Malt Extract, Soy Protein Isolate, Ultra-pasteurized Soy Sauce, Whey Protein Concentrate, Soy Protein Concentrate, Whey Protein Isolate, Protease Enzymes, Protein Fortified anything, Enzyme Modified anything and Citric Acid.

Glutamate in Vaccines

Both MSG and hydrolyzed gelatin (11% free glutamate by weight) are found in many vaccines. Considering the dangers associated with glutamate as well as the other alternative stabilizers available, it is not clear why vaccine manufacturers continue to incorporate these harmful ingredients in their formulas. Even a simple vaccine given to children such as the FluMist contains MSG (Source: FluMist February 2012 from fda.gov – page 12).

Another example would be Merck’s M-M-R vaccine. The product insert states that the growth medium for measles and mumps includes “amino acids” and “glutamate.” It is also stated that the medium for rubella included “amino acids” and “hydrolyzed gelatin.” Finally, it states that the “reconstituted vaccine” for subcutaneous administration includes hydrolyzed gelatin.

We also know that any hydrolyzed protein, such as the hydrolyzed gelatin will contain some processed free glutamic acid (MSG), some aspartic acid, and some L-cysteine, all considered to be neurotoxic by neuroscientists. Even without hydrolyzing gelatin, gelatin contains over 11% processed free glutamic acid (MSG) and some aspartic acid and L-cysteine. It is present as a result of the manufacturing process that results in gelatin.

A study on infant rats showed that administration of MSG lead to five shrunken glands, including the testes. Other studies have shown that growth hormone, thyroid hormones and many other endocrine functions can be assaulted by excitotoxins which may lead to growth retardation of children before the age of puberty.

Based on peer reviewed studies, there is no question that glutamic acid is neurotoxic. This can be easily confirmed by accessing MEDLINE retrieval service for studies dating from 1966 to the present, using the words “glutamic acid” in combination with the words “brain lesions” and then “neurotoxicity.”

There is also no question that the young are most at risk from MSG. The work of John W. Olney, MD has provided sufficient evidence on the effect of glutamic acid on the blood brain and placental barriers.

The Schizophrenic Connection

There are a number of straightforward bold faced lies used by the glutamate industry in defending its contention that exposure to free glutamic acid found in processed food does not cause adverse reactions including hives, asthma, seizures, and migraine headache; could not possibly cause brain damage, learning disorders, or endocrine disturbances; and could not possibly be relevant to diverse diseases of the central nervous system such as addiction, stroke, epilepsy, schizophrenia, anxiety, depression, and degenerative disorders such as ALS, Parkinson’s disease, and Alzheimer’s disease. Central to their argument is the lie that the processed free glutamic acid used in processed food is identical to the glutamic acid found in unprocessed, unadulterated food and in the human body.

The scientific evidence is now slowly surfacing that free glutamate is causing severe damage to brain chemistry.

To see if the increase in glutamate leads to brain changes, the researchers at Columbia University Medical Center (CUMC) turned to a mouse model of schizophrenia. When the researchers increased glutamate activity in the mouse, they saw the same pattern as in schizophrenic patients: The hippocampus became hypermetabolic and, if glutamate was raised repeatedly, the hippocampus began to atrophy.

Strategies are now being employed to treat schizophrenia by reducing glutamate. “Targeting glutamate may be more useful in high-risk people or in those with early signs of the disorder,” said Jeffrey A. Lieberman, MD, a renowned expert in the field of schizophrenia. “Early intervention may prevent the debilitating effects of schizophrenia, increasing recovery in one of humankind’s most costly mental disorders.”

If excess glutamate is driving schizophrenia, it may also explain why children begin having psychotic episodes at young ages often after multi-dose vaccines are administered, since this may directly increases glutamate levels in the brain of young children.

An increasing body of peer-reviewed evidence indicates that when a woman is pregnant, transiently elevated cytokines can induce atypical brain development in her embryo or fetus. Illnesses and vaccinations induce elevation of cytokines, and these elevations can be heightened in individuals with alleles of genes related to immune responses. An implication of citations supporting these relationships is that vaccinating pregnant women is likely to induce cognitive and behavioral pathologies in as least some children whose mothers were vaccinated while the child was in utero. Schizophrenia and developmental disabilities are pathologies that may ensue.

A pregnant woman’s options are discomforting. If she develops swine flu or seasonal influenza, she may induce cytokine elevations which adversely affect her fetus. If she allows herself to be vaccinated during pregnancy, her body’s reaction will include cytokine elevations which may adversely affect brain development of some fetuses – and do in ways that become apparent only during early childhood, adolescence, or young adulthood.

Since 100% of both routine and influenza vaccinations are not tested for long-term safety and effectiveness in pregnant women or nursing mothers, there is no conclusive scientific evidence available on their pharmacokinetic risks nor the physiological impact they may present in the development of schizophrenia and related psychotic disorders.

This area of study is worthy of serious investigation to firmly establish whether the foundation of the majority of glutamate associated psychotic disorders stem from dietary patterns and medical intervention (primarily vaccines) in early childhood.

Alert: You May Be Living in a Simulated Universe

By Geraint Lewis, University of Sydney | December 6, 2012

Physicist Proposes New Theory of Gravity—Gravity Does Not Exist

simulated

Universe’s Structure Similar to Human Brain and Internet

As a cosmologist, I often carry around a universe or two in my pocket. Not entire, infinitely large universes, but maybe a few billion light years or so across. Enough to be interesting.

Of course, these are not “real” universes; rather they are universes I have simulated on a computer.

The basic idea of simulating a universe is quite simple. You need “initial conditions” which, for me, is the state of the universe just after the Big Bang.

To this, you add the laws of physics, such as: how gravity pulls on mass, how gas flows into galaxies, and how stars are born, live and die.

You press “go”, and then sit back as the computer calculates all of the complex interactions, and evolves the universe over cosmic time.

A wonderful description by Andrew Pontzen on how astronomers synthesize and study their very own galaxies and universes.

What’s more fun is playing “Master of the Universe”, and messing about with the laws of physics, such as changing the properties of gravity, or how black holes swallow matter. Waiting to see the outcome of these mutated universes is always interesting.

I know in my heart that these universes are nothing more than ones and zeros buried within my computer, but in the movies I make of my evolving galaxies and clusters, and the one embedded further down in this article, I can see the mass moving around. It looks real!

Computer simulations of complex phenomena are everywhere in science, and cosmologists aren’t the only ones that marvel at synthetic chunks of the real universe.

It is equally inspiring to watch the flow of air around a newly-designed wing, or how individual molecules make their way through a biological membrane, and such simulations have revolutionized science.

Of course, these advances have only occurred with the growth of computer power over the last few decades, and the push is always towards the inclusion of more complex physics over an immense range of scales, from the cosmological to the quantum.

We are always limited by the power of computing, but as computers get bigger and faster, so does the detail within our synthetic universes.

“Cosmologists aren’t the only ones that marvel at synthetic chunks of the real universe.”

But let’s imagine a time in the future, a time when computers are powerful enough to fully simulate a human brain, with its vast array of interconnected neurons.

These neurons obey the laws of physics, and fire as their chemical balances change. Thoughts would echo around this synthetic brain, with electrical signals coursing backwards and forwards.

Not being a philosopher, I will ignore the (seemingly endless) debates about free will and consciousness, but if you take a purely mechanical view of the human brain, the synthetic brain will be as “alive” as the organic brain that made it.

Fed with the stimulus from a synthetic body interacting with a synthetic universe, it will experience pain and fear, happiness and love, even boredom and drowsiness.

There are, in fact, some that believe we will all be reborn in a glorious future, where computers are powerful enough to recreate everyone who has ever lived, and then sustain them for eternity.

While this vision of heaven is touted as the Final Anthropic Principle, some have more bluntly labelled it the “Completely Ridiculous Anthropic Principle”, or C.R.A.P. for short.

But we may not have to wait until the distant future!

“In simulations, I can see the mass moving around. It looks real!”

To quote the late, great Douglas Adams, “there is another theory which states that this has already happened”.

Not that someone on Earth, or even within our universe, has created a truly synthetic universe, complete with beings that are clueless to the fact they are nothing but part of a computer experiment.

No, the startling realization is that we, our very existence, every thing we have seen, have experienced, or will ever experience, could be nothing but the chugging of bits in an unimaginable supercomputer.

As I type this on a laptop, and stare out the train window at the station rolling past, at the people, the trees, the dirt on the ground, surely I would know if I was part of a computer program?

But then again, my brain is simply processing inputs, and if the simulated inputs fed into my simulated brain are good enough, how would I know?

It is important to remember that this picture is different to the “Brain-in-a-vat” presented in the Matrix movies. There, an organic brain is fed information, recreating the synthetic world in which the characters find themselves.

Instead, our picture is that there is no organic brain. We are part of the matrix itself.

So, how can we know if we are part of a computer simulation?

It is important to remember our earthly computers are limited in the way they can represent real numbers, holding only a finite number of digits for typical calculations.

What this means is that my simulated universes are quantized in some sense, with the limited resolution imprinted in the details of the structure that is produced.

If we are living in a computer simulation, then maybe such resolution effects are apparent to us. Our world doesn’t look like the Minecraft universe, and so we expect the resolution scale to be smaller than the scale of individual atoms, rather than large, foot-cubed blocks.

Just last month, researchers from the University of Bonn, Germany suggested we can detect such “chunkiness” of the small scale by looking how high-energy particles, known as cosmic rays, traverse huge distances in the universe. As these rays bounce through this space, their energy properties get modified, and by looking at what arrives on Earth, we can work out the size of the chunks.

But there are problems with this idea.

Firstly, we are working under the assumption that the computer we live in operates like an everyday computer. But these everyday computers are governed by the laws of physics of the synthetic universe in which we reside.

The unimaginably powerful computer that hosts our universe may operate in ways we cannot even think about.

The resolution scale of our universe is considerably smaller than in the “chunky” Minecraft universe.

Another problem is that those trying to understand the nature of the very small have already proposed a quantized backdrop of space and time in which we live.

Is the existence of such a space-time simply a property of a real universe, or the tell-tale sign of a synthetic one? How can we ever tell them apart? Do we even want to?

One way of potentially detecting the real nature of the universe is to search for the extraordinary – or, in the words of my children, who play video games, glitches–where the program doesn’t do as expected.

Perhaps some of the unexplained things we cannot yet explain are simply glitches in the program (although I am a fan of illusionist Derren Brown and think the human mind can be easily tricked).

The other alternative is more drastic.

When my synthetic universes are running, they can abruptly come to a halt for a variety of reasons, such as disk-space filling up, errors in the memory, or something as simple as the cleaner unplugging the computer to vacuum the floor.

If my synthetic universe is running when the power goes out, it simply ceases to exist.

I do hope the cleaners of our potential-hyperdimensional-universe-simulating overlords are more careful.

This article was originally published by The Conversation.