British Journal of Psychiatry

No Differences Seen In Defects, Doctors Say

UH, EXCUSE ME??????

Expectant mothers can safely use prescribed antidepressants during their first trimester, according to a new study from the Université de Montréal and Ste. Justine Hospital.

“This is the first study to investigate the impact of antidepressant use during the first trimester of pregnancy in mothers with psychiatric disorders,” said Dr. Anick Berard. “In terms of birth malformations in this population, we found no difference between women who used antidepressants and those who did not use antidepressants during their first trimester.”

The research team used data from the Quebec Pregnancy Registry to analyze the records of 2,329 new mothers diagnosed with a psychiatric disorder and treated with antidepressants for at least 30 days before pregnancy. The group included women who delivered live born and stillborn children, while birth defects were considered anything from facial malformations to heart anomalies.

“The duration of antidepressant use in the first trimester of pregnancy was not associated with an increased risk of birth malformations,” Berard said. “We hope these findings help clinicians and women decide whether to continue antidepressant therapy during pregnancy.”

The study was published in the May edition of the British Journal of Psychiatry.